Purine nucleosides
Medchemexpress LLC 2'-deoxyadenosine-5'-monophosphate | 653-63-4 | MFCD00005753 | 99.6% | 331.22 g/mol | C10H14N5O6P | 1 ML
2'-Deoxyadenosine-5'-monophosphate (dAMP) is a deoxynucleotide used in biochemical and molecular biology research as an adenine-containing monophosphate component of DNA. It is used to study DNA synthesis, nucleotide interactions, and DNA damage/repair. The compound is supplied as a solid and as a ready-to-use 10 mM solution in DMSO for assay use.
- Adenine nucleoside monophosphate for DNA research.
- Available as solid or 10 mM solution in DMSO for immediate use.
- High purity suitable for biochemical assays.
- Compatible with DNA synthesis and damage/repair studies.
- Formula C10H14N5O6P and molecular weight 331.22 g/mol; CAS 653-63-4 for identification.
Medchemexpress LLC 2'-deoxyadenosine-5'-monophosphate-d12 dilithium | 97.7% | 355.16 | C10D12Li2N5O6P | 1 MG
2'-Deoxyadenosine-5'-monophosphate-d12 (dilithium) is a deuterium-labeled form of 2'-deoxyadenosine-5'-monophosphate used as a research reagent to study DNA synthesis, nucleotide interactions, and isotope tracing by mass spectrometry or NMR. Supplied as the dilithium salt, it is intended for laboratory research use only.
- Isotopically labeled d12 for accurate mass-shift studies.
- Suitable for mass spectrometry and NMR applications.
- Dilithium salt form for improved solubility in selected buffers.
- High purity (97.7%) for reproducible experimental results.
- Compatible with nucleotide chemistry and DNA interaction studies.
Cayman Chemical 2-DeoxyadenosIn-5-monphos 1g
A derivative of AMP that has been used in the synthesis of novel photoaffinity labels for incorporation into DNA and to study adenosine-based interactions during DNA synthesis and DNA damage
Chem-Impex International, Inc. 2'-Deoxyadenosine monohydrate | 16373-93-6 | MFCD00149364 | 1G
2'-Deoxyadenosine monohydrate, 16373-93-6, MFCD00149364, 1G
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 25 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase through hydrogen bonding with residues like Glu201 and Asn243. This compound demonstrates moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Derivative of guanosine.
- Interacts with human purine nucleoside phosphorylase via hydrogen bonding.
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges.
- Useful for studying guanosine receptor mechanisms.
- Useful for studying purine metabolism.
- Displaces 50 nM [3H]-guanosine binding to rat brain membranes.
Medchemexpress LLC Malvidin-3-O-arabinoside chloride | 28500-04-1 | 97.1% | 498.86 | 5 MG
Malvidin-3-O-arabinoside chloride (M3A chloride) is a research chemical that ameliorates ethyl carbamate-induced oxidative damage by stimulating AMPK-mediated autophagy. It is used in studies to understand cellular processes related to oxidative stress and autophagy.
- Stimulates phosphorylation of AMP-activated protein kinase (AMPK)
- Upregulates LAMP-1 expression
- Restores lysosomal acidity and strengthens lysosomal functions
- Inhibits excess reactive oxygen species (ROS) generation
- Enhances glutathione (GSH) levels and autophagy flux
- Upregulates LC3-II/LC3-I ratio
Medchemexpress LLC N6-Threonylcarbamoyladenosine | 24719-82-2 | 99.6% | 412.35 | 1 MG
N6-Threonylcarbamoyladenosine is a common nucleoside that can decorate and become tRNA. It is for research use only.
- Purity of 99.62%
- Molecular weight of 412.35
- Chemical formula: C15H20N6O8
- Appearance: Solid
- Color: Off-white to light brown
- Storage conditions: -20°C for powder, -80°C for 6 months in solvent
Chem-Impex International, Inc. N2-Isobutyryl-2'-deoxyguanosine | 68892-42-2 | MFCD00010060 | 25G
N2-Isobutyryl-2'-deoxyguanosine, 68892-42-2, MFCD00010060, 25G
Chem-Impex International, Inc. 2'-Deoxyguanosine monohydrate | 961-07-9 | MFCD00150760 | 5G
2'-Deoxyguanosine monohydrate, 961-07-9, MFCD00150760, 5G
Sigma Aldrich Fine Chemicals Biosciences 2'-Deoxyguanosine monohydrate 99-100% | 312693-72-4 | MFCD00150760 | 25MG
2'-Deoxyguanosine monohydrate 99-100% | Purity: 99-100% | Mol Wt: 285.26 | 312693-72-4 | MFCD00150760 | 25MG
Cayman Chemical 5-chloro-5-DeoxyadenosIn 1g
A nucleoside analog used as a substrate in the biosynthesis of the anticancer agent salinosporamide A
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 25 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. This product is for research use only and not for sale to patients.
- Treatment results in rapid cell death for the vast majority of cancer cell lines tested, with IC50s between 0.7-2.9 μM.
- In A549 lung cancer cell-based mouse xenograft studies, it causes a decrease of the tumor growth rate, superior to that observed with 6-thioguanine treatment.
- It increases telomere dysfunction in tumor cells in vivo.
Cayman Chemical N6-Methyl-2-deoxyadenosIn 50mg
A nucleoside and inducer of EPC proliferation; stimulates the proliferation of EPCs isolated from mouse fetal livers and colony formation of isolated mouse bone marrow cell-derived progenitor cells at 10 and 100 µM; accumulates along promoters and gene coding sequences in activated mouse prefrontal cortical neurons; is associated with activation at the Bdnf promoter
Medchemexpress LLC 8-Bromo-2'-deoxyadenosine | 14985-44-5 | ≥98.0% | 330.14 | 100 MG
8-Bromo-2'-deoxyadenosine is a purine nucleoside analog. These analogs possess broad antitumor activity against indolent lymphoid malignancies. Their anticancer mechanisms involve the inhibition of DNA synthesis and the induction of apoptosis.
- Purine nucleoside analog
- Broad antitumor activity
- Inhibits DNA synthesis
- Induces apoptosis